Token & Model
Ethereum 2.0’s token is known as ETH, and uses a sharded, fixed function STF model.
Cosmos’s token is an ATOM, and its model is the bridge-hub.
Ethereum 2.0’s consensus protocol is serenity.
Cosmos’s consensus protocol is Tendermint.
Block Production Sub-protocol
Ethereum 2.0’s block production sub-protocol is RanDAO + LMD Casper.
Cosmos is monolithic so it does not have a block production sub-protocol.
Finality Gadget Sub-protocol
Ethereum 2.0’s finality gadget sub-protocol is Casper FFG.
Cosmos is monolithic so it does not have a finality gadget sub-protocol.
Main Chain Name
Ethereum 2.0’s main chain name is Beacon Chain.
Cosmos’s main chain name is Cosmos Hub.
Interior Chains Name
Ethereum 2.0’s Interior chain name is Shard.
Cosmos is not sharded, so there is no interior chain.
Exterior Chains Name
Ethereum 2.0’s Exterior chain name is Side-chain.
Cosmos’s exterior chain is called Zone.
 Technically, there’s little to prevent other “main chains” on the network if they can get enough buy-in.